SCHEMBL6293182

SCHEMBL6293182

CCc1cccc(F)c1Oc1ccccc1Oc1ccccc1Oc1ccccc1Oc1ccccc1Oc1c(F)cccc1CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCL8 P10145 2/20 0.46
SLC6A2 P23975 6/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
HTR1A P08908 3/20 0.40
MAPT P10636 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
SLC6A4 P31645 3/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6289913 0.91 SLC6A4 (0.43) CXCL8SLC6A2L3MBTL1MAPTNPSR1
SCHEMBL6290765 0.79 ALDH1A1 (0.44) SLC6A2L3MBTL1MAPTNPSR1SLC6A4
SCHEMBL12648278 0.77 SLC6A2 (0.43) SLC6A2L3MBTL1MAPTSLC6A4ALDH1A1
SCHEMBL11361204 0.76 GABRA1 (0.52) L3MBTL1HTR1AMAPTNPSR1KCNH2
SCHEMBL23251431 0.76 L3MBTL1 (0.43) SLC6A2L3MBTL1MAPTNPSR1SLC6A4
SCHEMBL475213 0.74 L3MBTL1 (0.57) CXCL8SLC6A2L3MBTL1MAPTNPSR1
SCHEMBL13794212 0.73 MAOB (0.44) L3MBTL1MAPTNPSR1ALDH1A1KDM4E
SCHEMBL28823867 0.73 GABRA1 (0.38) SLC6A2SLC6A4ALDH1A1KDM4E
SCHEMBL22474450 0.73 GABRA1 (0.42) SLC6A2L3MBTL1MAPTNPSR1SLC6A4
SCHEMBL11919265 0.73 DHODH (0.41) SLC6A2SLC6A4ALDH1A1SLC6A3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6933411-B2 Aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2005-08-23 US disclosed
US-6737503-B2 LOW TEMPERATURE ADHESIVE BONDING MITSUI CHEMICALS, INC. (JP) 2004-05-18 US disclosed
US-20040082754-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2004-04-29 US disclosed
US-20030092870-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
EP-1288191-A2 Novel aromatic diamine and polyimide thereof Mitsui Chemicals, Inc. (JP) 2003-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092870-A1 Novel aromatic diamine and polyimide thereof DDT, AOC1, H1-4 CXCL8 2709/4885SLC6A2 2617/4885L3MBTL1 2546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.