Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318218 | 0.93 | APP (0.38) | APP | |
| Hydrochloric Acid SCHEMBL9619840 | 0.90 | APP (0.36) | APP | |
| Hydrochloric Acid SCHEMBL9619839 | 0.88 | APP (0.35) | APP | |
| SCHEMBL1261913 | 0.78 | APP (0.35) | APP | |
| SCHEMBL3795554 | 0.75 | LSS (0.40) | — | |
| SCHEMBL10564377 | 0.72 | CA12 (0.48) | — | |
| SCHEMBL6297073 | 0.72 | CA12 (0.48) | — | |
| SCHEMBL11409076 | 0.72 | CA12 (0.48) | — | |
| Hydrochloric Acid SCHEMBL10952910 | 0.72 | ALDH1A1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL10823280 | 0.70 | GLA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6955921-B2 | Trypsin substrate and diagnostic device, and method of using same | BAYER CORPORATION (US) | 2005-10-18 | — | — | US | disclosed |
| US-6770764-B2 | DIAGNOSIS OF BACTERIA INFECTIONS | BAYER CORPORATION | 2004-08-03 | — | — | US | disclosed |
| US-20030125577-A1 | Trypsin substrate and diagnostic device, and method of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2003-07-03 | — | — | US | disclosed |
| US-20020004219-A1 | Trypsin substrate and diganostic device, and method of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2002-01-10 | — | — | US | disclosed |
| EP-1157984-A2 | Trypsin substrate and diagnostic device, and method of using same | Bayer Corporation (US) | 2001-11-28 | — | — | EP | disclosed |
| US-4749648-A | Agent for the determination of esterolytic and/or proteolytic enzymes | BOEHRINGER MANNHEIM GMBH (DE) | 1988-06-07 | — | — | US | disclosed |
| US-4551428-A | COLORIMETRIC ANALYSIS USING DIAZONIUM COUPLERS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-11-05 | — | — | US | disclosed |
| EP-0039880-A1 | Agents for the detection of esterolytic and/or proteolytic enzymes; and phenoxy-amino acids and phenoxy-peptide esters suitable as substrates therefor, process for their production and their use in producing the agents | Roche Diagnostics GmbH (DE) | 1981-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004219-A1 | Trypsin substrate and diganostic device, and method of using same | PRSS3, CTRL, PRSS2 | APP 654/4885 |
| US-20030125577-A1 | Trypsin substrate and diagnostic device, and method of using same | CTRL, PRSS3, SPINT2 | APP 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.