Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27849783 | 0.83 | BACE1 (0.47) | ESR2PDCD1CD274CYP2A6CYP2B6 | |
| SCHEMBL5951481 | 0.83 | MAPT (0.44) | ESR2CYP2A6CYP2B6ALDH1A1MAPT | |
| SCHEMBL2558217 | 0.79 | LMNA (0.47) | ESR2PDCD1CD274CYP2A6CYP2B6 | |
| SCHEMBL4651266 | 0.79 | ESR2 (0.44) | ESR2PDCD1CD274CYP2A6CYP2B6 | |
| SCHEMBL4651268 | 0.79 | ALDH1A1 (0.43) | ESR2PDCD1CD274CYP2A6CYP2B6 | |
| SCHEMBL29027489 | 0.78 | ESR2 (0.42) | ESR2PDCD1CD274CYP2A6CYP2B6 | |
| SCHEMBL29629488 | 0.78 | LMNA (0.46) | ESR2PDCD1CD274CYP2A6CYP2B6 | |
| Hydrogen Sulfide SCHEMBL27610664 | 0.78 | LMNA (0.46) | ESR2PDCD1CD274CYP2A6CYP2B6 | |
| SCHEMBL3362430 | 0.76 | ALDH1A1 (0.41) | ESR2PDCD1CD274CYP2A6CYP2B6 | |
| SCHEMBL6838773 | 0.75 | ESR2 (0.44) | ESR2PDCD1CD274CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108008600-B | Radiation-sensitive composition | 三菱瓦斯化学株式会社 | 2021-02-09 | — | — | CN | disclosed |
| CN-101445518-B | Preparation method of phosphine ligand | SHANGHAI RECORD PHARMACEUTICALS CO LTD | 2012-09-05 | — | — | CN | disclosed |
| CN-101747125-B | Methods for preparing biaryl compound and diolefin compound | CHANGCHUN APPLIED CHEMISTRY | 2012-09-05 | — | — | CN | disclosed |
| CN-101747125-A | Methods for preparing biaryl compound and diolefin compound | CHANGCHUN APPLIED CHEMISTRY | 2010-06-23 | — | — | CN | disclosed |
| CN-101445518-A | Preparation method of phosphine ligand and method for phosphine ligand to catalyze and synthetize biaryl and derivatives thereof | SHANGHAI RECORD PHARMACEUTICAL (CN) | 2009-06-03 | — | — | CN | disclosed |
| US-6914119-B2 | Heat-resistant polyether, curable polyether, and coating liquid for forming a polyether film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-05 | — | — | US | disclosed |
| US-20030060591-A1 | Heat-resistant polyether, curable polyether, and coating liquid for forming a polyether film | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060591-A1 | Heat-resistant polyether, curable polyether, and coating liquid for forming a polyether film | HEATR1, HSP90AA1, HEATR6 | ESR2 755/4885PDCD1 2742/4885CD274 1317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.