Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 9/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294972 | 0.87 | PLAU (0.47) | SLC22A12PLA2G7SCN9ATRIM24PLAU | |
| Trifluoroacetic Acid SCHEMBL7150670 | 0.85 | PLA2G7 (0.41) | SLC22A12PLA2G7SCN9A | |
| Trifluoroacetic Acid SCHEMBL7150647 | 0.75 | PLA2G7 (0.44) | SLC22A12PLA2G7 | |
| Trifluoroacetic Acid SCHEMBL7157237 | 0.73 | PLA2G7 (0.39) | SLC22A12PLA2G7SCN9APLAU | |
| SCHEMBL6295040 | 0.72 | BRD4 (0.43) | SLC22A12PLA2G7SCN9A | |
| Trifluoroacetic Acid SCHEMBL7150674 | 0.71 | PLA2G7 (0.37) | SLC22A12PLA2G7SCN9A | |
| Trifluoroacetic Acid SCHEMBL7153794 | 0.69 | BRD4 (0.40) | PLA2G7SCN9A | |
| SCHEMBL17654333 | 0.66 | SLC6A2 (0.52) | — | |
| Trifluoroacetic Acid SCHEMBL7155223 | 0.65 | PLA2G7 (0.43) | SLC22A12PLA2G7PLAU | |
| SCHEMBL8475188 | 0.65 | PRSS1 (0.44) | PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |