Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7153794 | 0.89 | BRD4 (0.40) | PLA2G7SCN9ABRD4TBXA2R | |
| Trifluoroacetic Acid SCHEMBL7150670 | 0.88 | PLA2G7 (0.41) | PLA2G7SCN9ASLC22A12 | |
| Trifluoroacetic Acid SCHEMBL7155334 | 0.86 | PLA2G7 (0.40) | PLA2G7MCL1BRD4TBXA2RSLC22A12 | |
| Trifluoroacetic Acid SCHEMBL7157237 | 0.86 | PLA2G7 (0.39) | PLA2G7SCN9ASLC22A12MEN1KMT2A | |
| SCHEMBL6295040 | 0.84 | BRD4 (0.43) | PLA2G7SCN9ABRD4SLC22A12 | |
| Trifluoroacetic Acid SCHEMBL7155223 | 0.74 | PLA2G7 (0.43) | PLA2G7SLC22A12MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7153144 | 0.74 | BRD4 (0.43) | PLA2G7SCN9ABRD4 | |
| Trifluoroacetic Acid SCHEMBL7150647 | 0.73 | PLA2G7 (0.44) | PLA2G7SLC22A12MEN1MAPTKMT2A | |
| SCHEMBL6300729 | 0.71 | SLC22A12 (0.43) | PLA2G7SCN9ASLC22A12 | |
| Trifluoroacetic Acid SCHEMBL6300704 | 0.70 | PLA2G7 (0.47) | PLA2G7MEN1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |