Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7153794 | 0.95 | BRD4 (0.40) | BRD4SCN9APLA2G7NR3C1PGR | |
| Trifluoroacetic Acid SCHEMBL7150674 | 0.84 | PLA2G7 (0.37) | BRD4SCN9APLA2G7SLC22A12 | |
| Trifluoroacetic Acid SCHEMBL7157237 | 0.84 | PLA2G7 (0.39) | SCN9APLA2G7SLC22A12 | |
| Trifluoroacetic Acid SCHEMBL7150670 | 0.83 | PLA2G7 (0.41) | SCN9APLA2G7SLC22A12 | |
| Trifluoroacetic Acid SCHEMBL7153144 | 0.79 | BRD4 (0.43) | BRD4SCN9APLA2G7PGRAR | |
| SCHEMBL6295804 | 0.74 | ALDH1A1 (0.40) | SCN9AXDH | |
| Trifluoroacetic Acid SCHEMBL6296006 | 0.74 | BRD4 (0.43) | BRD4SCN9APLA2G7 | |
| SCHEMBL6294972 | 0.73 | PLAU (0.47) | SCN9APLA2G7SLC22A12 | |
| SCHEMBL8506169 | 0.72 | F3 (0.57) | — | |
| SCHEMBL6300729 | 0.72 | SLC22A12 (0.43) | SCN9APLA2G7SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |