Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 5/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30709850 | 0.81 | PNMT (0.65) | PNMTADRA2AMAPTLMNAMEN1 | |
| SCHEMBL9483063 | 0.81 | PNMT (0.65) | PNMTADRA2AMAPTLMNAMEN1 | |
| SCHEMBL8762150 | 0.79 | PNMT (0.50) | PNMTADRA2AMAPTLMNAMEN1 | |
| SCHEMBL2083495 | 0.77 | PNMT (0.61) | PNMTADRA2AMAPTLMNAMEN1 | |
| SCHEMBL1715396 | 0.77 | PNMT (0.61) | PNMTADRA2AMAPTLMNAMEN1 | |
| SCHEMBL467557 | 0.76 | PNMT (0.59) | PNMTADRA2AMAPTLMNAMEN1 | |
| SCHEMBL467503 | 0.74 | PNMT (0.57) | PNMTADRA2AMAPTLMNAMEN1 | |
| SCHEMBL717840 | 0.73 | PNMT (0.81) | PNMTADRA2AMAPTLMNAMEN1 | |
| SCHEMBL2061267 | 0.73 | PNMT (0.56) | PNMTADRA2AMAPTLMNAMEN1 | |
| SCHEMBL1098412 | 0.71 | TDP2 (0.51) | PNMTADRA2AMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972286-B2 | Oxazolidinones having a benzannulated 6- or 7-membered heterocycle | PHARMACIA AND UPJOHN COMPANY (US) | 2005-12-06 | — | — | US | disclosed |
| US-20040186293-A1 | Oxazolidinones having a benzannulated 6- or 7-membered heterocycle | JOHNSON PAUL D (US) | 2004-09-23 | — | — | US | disclosed |
| US-20040176609-A1 | Oxazolidinones having a benzannulated 6- or 7-membered heterocycle | JOHNSON PAUL D (US) | 2004-09-09 | — | — | US | disclosed |
| EP-1337530-A1 | OXAZOLIDINONES HAVING A BENZANNULATED 6-OR 7-MEMBERED HETEROCYCLE AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company (US) | 2003-08-27 | — | — | EP | disclosed |
| US-20020133021-A1 | Oxazolidinones having a benzannulated 6- or 7-membered heterocycle | PHARMACIA & UPJOHN COMPANY | 2002-09-19 | — | — | US | disclosed |
| WO-2002059115-A1 | OXAZOLIDINONES HAVING A BENZANNULATED 6-OR 7-MEMBERED HETEROCYCLE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020133021-A1 | Oxazolidinones having a benzannulated 6- or 7-membered heterocycle | OXA1L, CDK16, MT-ND6 | PNMT 4235/4885ADRA2A 4476/4885MAPT 4357/4885 |
| US-20040186293-A1 | Oxazolidinones having a benzannulated 6- or 7-membered heterocycle | OXA1L, CDK16, MT-ND6 | PNMT 4235/4885ADRA2A 4476/4885MAPT 4357/4885 |
| US-20040176609-A1 | Oxazolidinones having a benzannulated 6- or 7-membered heterocycle | OXA1L, CDK16, MT-ND6 | PNMT 4235/4885ADRA2A 4476/4885MAPT 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.