Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 7/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295392 | 0.79 | PNMT (0.50) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL30709850 | 0.77 | PNMT (0.65) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL9483063 | 0.77 | PNMT (0.65) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL30049268 | 0.75 | TLR9 (0.79) | PNMTADRA2ALMNAMEN1MAPT | |
| Ammonia Solution, Strong SCHEMBL27905491 | 0.75 | LMNA (0.62) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL987760 | 0.75 | TLR9 (0.79) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL2083495 | 0.73 | PNMT (0.61) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL1715396 | 0.73 | PNMT (0.61) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL7539847 | 0.73 | PNMT (0.51) | PNMTADRA2ALMNAMEN1MAPT | |
| SCHEMBL6891893 | 0.73 | PNMT (0.51) | PNMTADRA2ALMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698580-A | TREATING DISEASES CAUSED BY RESPIRATORY SYNCYTIAL VIRUS | RATIONAL DRUG DESIGN LABORATORIES (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0770609-A1 | ANTIVIRAL AGENT CONTAINING BENZODITHIIN DERIVATIVE AS ACTIVE INGREDIENT | Rational Drug Design Laboratories (JP) | 1997-05-02 | — | — | EP | disclosed |