SCHEMBL629655

SCHEMBL629655

O=C1C=CC(=O)N1.O=C1CCC(=O)N1O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.52
GSK3B P49841 1/20 0.52
CCR6 P51684 1/20 0.52
KDM4E B2RXH2 2/20 0.31
GAA P10253 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16694538 0.91 GSK3A (0.48) GSK3AGSK3BCCR6
Acetic Acid SCHEMBL28849017 0.90 GSK3A (0.42) GSK3AGSK3BCCR6
Benzoic Acid SCHEMBL27698997 0.82 DAO (0.45) GSK3AGSK3BCCR6KDM4EPOLB
SCHEMBL6270994 0.82
SCHEMBL1123 0.79
SCHEMBL338264 0.79 KDM4E (0.34) KDM4EGAAPOLB
SCHEMBL785147 0.79
SCHEMBL8665043 0.76 GSK3A (0.52) GSK3AGSK3BCCR6
SCHEMBL23174460 0.76
SCHEMBL21409686 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3262185-B1 DNA DISPLAY AND METHODS THEREOF UNIV HONG KONG (CN) 2020-08-26 EP claimed
EP-3262185-A1 DNA DISPLAY AND METHODS THEREOF The University of Hong Kong (CN) 2018-01-03 EP claimed
WO-2016134521-A1 DNA DISPLAY AND METHODS THEREOF THE UNIVERSITY OF HONG KONG (CN) 2016-09-01 WO claimed
EP-0810876-B1 INFLUENZA VIRUS SUBUNIT CONJUGATES AVENTIS PASTEUR INC (US) 2008-05-07 EP claimed
US-20240197846-A1 Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof CUE BIOPHARMA, INC. 2024-06-20 US disclosed
US-20240189403-A1 Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof CUE BIOPHARMA, INC. 2024-06-13 US disclosed
US-12006348-B2 T-cell modulatory multimeric polypeptide with conjugation sites and methods of use thereof CUE BIOPHARMA, INC. (US) 2024-06-11 US disclosed
US-20240175034-A1 FN3 DOMAIN-SIRNA CONJUGATES AND USES THEREOF Aro Biotherapeutics Company (US) 2024-05-30 US disclosed
WO-2024086713-A1 FN3 DOMAIN-SIRNA CONJUGATES AND USES THEREOF Aro Biotherapeutics Company (US) 2024-04-25 WO disclosed
EP-4350330-A1 NANOPARTICLE BODY, METHOD FOR PRODUCING SAME, AND NANOPARTICLE BODY COMPOSITION CONTAINING NANOPARTICLE BODY PHC Holdings Corporation (JP) 2024-04-10 EP disclosed
US-20240082411-A1 T-Cell Modulatory Polypeptides with Conjugation Sites and Methods of Use Thereof CUE BIOPHARMA, INC. 2024-03-14 US disclosed
US-20240043844-A1 FN3 Domain-siRNA Conjugates with Enzyme Replacement Therapy Aro Biotherapeutics Company 2024-02-08 US disclosed
US-20080176769-A1 Articles having localized molecules disposed thereon and methods of producing same PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2008-07-24 US disclosed
US-20080050747-A1 Articles having localized molecules disposed thereon and methods of producing and using same PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 2008-02-28 US disclosed
US-20080032301-A1 Articles having localized molecules disposed thereon and methods of producing same PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2008-02-07 US disclosed
EP-1540341-A4 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES UNIV ROCHESTER MEDICAL CT (US) 2007-01-10 EP disclosed
US-20060166295-A1 Method for determination of likelihood of occurrence of preterm labor in pregnant females NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2006-07-27 US disclosed
EP-1540341-A1 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES The University of Rochester Medical Center (US) 2005-06-15 EP disclosed
WO-2004003555-A1 METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES UNIVERSITY OF ROCHESTER MEDICAL CENTER (US) 2004-01-08 WO disclosed
WO-1991004273-A2 NOVEL PEPTIDES ASSOCIATED WITH THE CD4 BINDING REGION OF GP120 AND THEIR METHODS OF USE IDEC PHARMACEUTICALS CORP. (US) 1991-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12006348-B2 T-cell modulatory multimeric polypeptide with conjugation sites and methods of use thereof IL2, CD4, HLA-DRB1 GSK3A 3211/4885GSK3B 2660/4885CCR6 208/4885
US-20240175034-A1 FN3 DOMAIN-SIRNA CONJUGATES AND USES THEREOF FN1, ITGB3, FNIP1 GSK3A 2898/4885GSK3B 3002/4885CCR6 1383/4885
US-20240043844-A1 FN3 Domain-siRNA Conjugates with Enzyme Replacement Therapy FN1, TIMP3, DNASE1L3 GSK3A 2138/4885GSK3B 2294/4885CCR6 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.