Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 9/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631075 | 0.88 | FKBP1A (0.43) | FKBP1APKMTDP1LMNAPOLB | |
| SCHEMBL631233 | 0.86 | FKBP1A (0.46) | FKBP1APKMTDP1LMNAPOLB | |
| SCHEMBL629939 | 0.86 | CCR4 (0.43) | FKBP1APKMTDP1LMNAITGB1 | |
| SCHEMBL1384306 | 0.85 | FKBP1A (0.56) | AKR1C3FKBP1APKMTDP1LMNA | |
| SCHEMBL630070 | 0.85 | FKBP1A (0.56) | AKR1C3FKBP1APKMTDP1LMNA | |
| SCHEMBL630007 | 0.83 | FKBP1A (0.48) | FKBP1ATDP1LMNA | |
| SCHEMBL630470 | 0.83 | MEN1 (0.48) | FKBP1APKMTDP1LMNAPOLB | |
| SCHEMBL631251 | 0.82 | ALDH1A1 (0.49) | FKBP1APKMTDP1ALDH1A1MAPK1 | |
| SCHEMBL631194 | 0.81 | ITGB1 (0.47) | FKBP1APKMTDP1LMNAITGB1 | |
| SCHEMBL630767 | 0.78 | ITGB1 (0.46) | FKBP1APKMTDP1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |