Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 10/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631469 | 0.90 | ALDH1A1 (0.44) | ITGB1ITGA5NPSR1ALDH1A1MAPK1 | |
| SCHEMBL630266 | 0.88 | ITGB1 (0.49) | ITGB1ITGA5NPSR1ALDH1A1MAPK1 | |
| SCHEMBL630786 | 0.84 | TDP1 (0.46) | NPSR1ALDH1A1MAPK1FKBP1APKM | |
| SCHEMBL631343 | 0.83 | PKM (0.43) | NPSR1ALDH1A1MAPK1FKBP1APKM | |
| SCHEMBL631194 | 0.83 | ITGB1 (0.47) | ITGB1ITGA5NPSR1ALDH1A1MAPK1 | |
| SCHEMBL631775 | 0.81 | LMNA (0.47) | ALDH1A1PKMLMNAMAPT | |
| SCHEMBL631233 | 0.80 | FKBP1A (0.46) | ITGB1ITGA5NPSR1ALDH1A1MAPK1 | |
| SCHEMBL630023 | 0.78 | AKR1C3 (0.44) | ITGB1ITGA5NPSR1ALDH1A1MAPK1 | |
| SCHEMBL630470 | 0.78 | MEN1 (0.48) | ITGB1ITGA5NPSR1ALDH1A1MAPK1 | |
| SCHEMBL631075 | 0.77 | FKBP1A (0.43) | ITGB1ITGA5FKBP1APKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |