Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.37 |
| ▸ | ITGAV | P06756 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300242 | 0.77 | ALDH1A1 (0.35) | TPSAB1TPSD1TPSG1ITGB3ITGAV | |
| SCHEMBL6300679 | 0.77 | BDKRB1 (0.39) | ITGB3ITGAVITGA2B | |
| SCHEMBL6308297 | 0.75 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL6302598 | 0.75 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| Trifluoroacetic Acid SCHEMBL6302651 | 0.74 | BDKRB1 (0.37) | ITGB3ITGAVITGA2B | |
| SCHEMBL6301697 | 0.73 | ITGB3 (0.52) | ITGB3ITGAVITGA2B | |
| Trifluoroacetic Acid SCHEMBL6300648 | 0.72 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| Trifluoroacetic Acid SCHEMBL6300360 | 0.69 | ITGB3 (0.48) | ITGB3ITGAVITGA2B | |
| SCHEMBL6300576 | 0.68 | ITGB3 (0.43) | TPSAB1TPSD1TPSG1ITGB3ITGAV | |
| SCHEMBL6308242 | 0.66 | ITGB3 (0.48) | TPSAB1TPSD1TPSG1ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846833-B2 | Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same | LES LABORATORIES SERVIER (FR) | 2005-01-25 | — | — | US | disclosed |