Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.43 |
| ▸ | ITGAV | P06756 | 5/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308242 | 0.85 | ITGB3 (0.48) | ITGB3ITGAVITGA2BITGB5MEN1 | |
| Trifluoroacetic Acid SCHEMBL6307546 | 0.82 | ITGB3 (0.45) | ITGB3ITGAVITGA2BITGB5MEN1 | |
| SCHEMBL6300679 | 0.79 | BDKRB1 (0.39) | ITGB3ITGAVITGA2BITGB5BDKRB1 | |
| Trifluoroacetic Acid SCHEMBL6302651 | 0.75 | BDKRB1 (0.37) | ITGB3ITGAVITGA2BITGB5BDKRB1 | |
| SCHEMBL6307550 | 0.74 | TRPM8 (0.38) | ITGB3ITGAVITGA2BITGB5MEN1 | |
| SCHEMBL6301697 | 0.73 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6302598 | 0.72 | ITGB3 (0.57) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6308297 | 0.72 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6306650 | 0.71 | WDR5 (0.64) | WDR5 | |
| SCHEMBL6300242 | 0.70 | ALDH1A1 (0.35) | ITGB3ITGAVMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846833-B2 | Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same | LES LABORATORIES SERVIER (FR) | 2005-01-25 | — | — | US | disclosed |
| EP-1268429-B1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-08-18 | — | — | EP | disclosed |