Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.37 |
| ▸ | ITGAV | P06756 | 4/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6302651 | 0.95 | BDKRB1 (0.37) | BDKRB1ADRA1DADRA1AADRA1BITGB3 | |
| SCHEMBL6302652 | 0.87 | BDKRB1 (0.38) | BDKRB1ADRA1DADRA1AADRA1BITGB3 | |
| SCHEMBL6300242 | 0.83 | ALDH1A1 (0.35) | ITGB3ITGAV | |
| SCHEMBL6302598 | 0.79 | ITGB3 (0.57) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6308297 | 0.79 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6300576 | 0.79 | ITGB3 (0.43) | BDKRB1ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6300245 | 0.77 | TPSAB1 (0.37) | ITGB3ITGAVITGA2B | |
| SCHEMBL6301697 | 0.77 | ITGB3 (0.52) | ITGB3ITGAVITGA2BITGB5 | |
| Trifluoroacetic Acid SCHEMBL6300648 | 0.76 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5 | |
| Trifluoroacetic Acid SCHEMBL6300360 | 0.73 | ITGB3 (0.48) | ITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846833-B2 | Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same | LES LABORATORIES SERVIER (FR) | 2005-01-25 | — | — | US | disclosed |
| EP-1268429-B1 | VITRONECTIN RECEPTOR ANTAGONIST BICYCLIC COMPOUNDS, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2004-08-18 | — | — | EP | disclosed |