Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300242 | 0.87 | ALDH1A1 (0.35) | ALDH1A1KDM4ESMN1; SMN2GAAMEN1 | |
| SCHEMBL6302652 | 0.85 | BDKRB1 (0.38) | LMNABDKRB1ADRA1DADRA1AADRA1B | |
| SCHEMBL6300654 | 0.81 | ITGB3 (0.43) | — | |
| SCHEMBL6300365 | 0.79 | TRPM8 (0.41) | — | |
| SCHEMBL6565439 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2GAAMEN1 | |
| SCHEMBL6307550 | 0.72 | TRPM8 (0.38) | ALDH1A1MEN1KMT2AF2 | |
| SCHEMBL6300679 | 0.71 | BDKRB1 (0.39) | BDKRB1ADRA1DADRA1AADRA1B | |
| Trifluoroacetic Acid SCHEMBL6300648 | 0.69 | ITGB3 (0.53) | — | |
| Trifluoroacetic Acid SCHEMBL6300360 | 0.67 | ITGB3 (0.48) | F2 | |
| SCHEMBL6302598 | 0.66 | ITGB3 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846833-B2 | Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same | LES LABORATORIES SERVIER (FR) | 2005-01-25 | — | — | US | disclosed |