Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.70 |
| ▸ | TUBB | P07437 | 1/20 | 0.70 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.70 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.70 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.70 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.70 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.70 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.70 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.70 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.70 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.70 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.70 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.70 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.70 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790294 | 0.91 | GAA (0.86) | GAALMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19000410 | 0.86 | PGR (0.67) | GAALMNAMAPK1TUBB4ATUBB | |
| SCHEMBL32679643 | 0.86 | GAA (0.78) | GAALMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1592323 | 0.86 | UQCRB (0.76) | GAALMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30434229 | 0.85 | GAA (0.76) | GAALMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7564170 | 0.85 | GAA (0.76) | GAALMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL806437 | 0.85 | GAA (0.76) | GAALMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29031235 | 0.85 | PGR (0.85) | GAALMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8752410 | 0.83 | GAA (0.73) | GAALMNAMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2240982 | 0.83 | LMNA (0.73) | GAALMNAMAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080631-A | Method for preparing N-aryl amide compound by catalyzing nitrite-mediated selenium | 浙江工业大学 | 2024-12-06 | — | — | CN | disclosed |
| EP-3334713-B1 | PHENYLSULFONAMIDO-BENZOFURAN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF PROLIFERATIVE DISEASES | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-07-21 | — | — | EP | disclosed |
| US-10975051-B2 | Phenylsulfonamido-benzofuran derivatives and uses thereof in the treatment of proliferative diseases | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-04-13 | — | — | US | disclosed |
| US-6921740-B1 | Electron-receiving compound and thermal recording material | MITSUBISHI PAPER MIILS LTD. (JP) | 2005-07-26 | — | — | US | disclosed |
| US-6579829-B2 | Aromatic sulfonamide compound | MITSUI CHEMICALS, INC. (JP) | 2003-06-17 | — | — | US | disclosed |
| EP-1138517-A2 | Developer composition and heat sensitive recording material | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975051-B2 | Phenylsulfonamido-benzofuran derivatives and uses thereof in the treatment of proliferative diseases | BCL2L1, BCL2, BCLAF1 | GAA 2954/4885LMNA 2043/4885MAPK1 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.