Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296162 | 0.88 | NAMPT (0.57) | NAMPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3334590 | 0.77 | MGLL (0.52) | NAMPTALDH1A1SMN1; SMN2HTTVCP | |
| SCHEMBL10639382 | 0.75 | VCP (0.50) | ALDH1A1SMN1; SMN2VCPGAATDP1 | |
| SCHEMBL4798640 | 0.75 | VCP (0.50) | ALDH1A1SMN1; SMN2VCPGAATDP1 | |
| Ammonia Solution, Strong SCHEMBL4804478 | 0.74 | VCP (0.49) | ALDH1A1SMN1; SMN2VCPGAATDP1 | |
| SCHEMBL6302405 | 0.74 | EPHX1 (0.73) | NAMPTMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6301912 | 0.72 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14633632 | 0.72 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5450458 | 0.72 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14534739 | 0.72 | ALDH1A1 (0.54) | NAMPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |