Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.49 |
| ▸ | MMP2 | P08253 | 7/20 | 0.49 |
| ▸ | MMP14 | P50281 | 4/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368387 | 0.89 | ITGB1 (0.60) | MMP2ITGB1ITGA4ITGB7ITGB2 | |
| SCHEMBL8268055 | 0.83 | ITGB2 (0.51) | ITGB2ICAM1ITGALGHSRDPP3 | |
| SCHEMBL13206955 | 0.81 | ITGB2 (0.52) | ITGB1ITGB2ICAM1ITGALDPP3 | |
| SCHEMBL631002 | 0.81 | ITGB2 (0.52) | ITGB1ITGB2ICAM1ITGALDPP3 | |
| SCHEMBL629768 | 0.81 | ITGB2 (0.52) | ITGB1ITGB2ICAM1ITGALDPP3 | |
| SCHEMBL630229 | 0.81 | MMP9 (0.54) | MMP2MMP14ITGB1ITGB2ICAM1 | |
| SCHEMBL7069023 | 0.78 | ALOX5 (0.59) | MMP2ITGB1ITGA4ITGB2ICAM1 | |
| SCHEMBL629890 | 0.78 | HDAC2 (0.48) | MMP1MMP2MMP14MMP9MMP3 | |
| SCHEMBL1383357 | 0.78 | HDAC2 (0.48) | MMP1MMP2MMP14MMP9MMP3 | |
| SCHEMBL630909 | 0.78 | MMP9 (0.48) | MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |
| JP-4812758-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | disclosed |
| US-7777042-B2 | N-sulfonylpipecolic acid derivative FKBP binding composition and pharmaceutical use thereof | AVENTIS PHARMACEUTICALS INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-7777042-B2 | N-sulfonylpipecolic acid derivative FKBP binding composition and pharmaceutical use thereof | AVENTIS PHARMACEUTICALS INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20080139556-A1 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2008-06-12 | — | — | US | disclosed |
| US-20080139556-A1 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139556-A1 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | FKBP1A, FKBP1B, FKBP3 | MMP1 4649/4885MMP2 4150/4885MMP14 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.