Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.38 |
| ▸ | ITGAL | P20701 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KRAS | P01116 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381877 | 0.88 | ITGB2 (0.42) | SNCASOS1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL631775 | 0.85 | LMNA (0.47) | SOS1ALDH1A1MAPTSMN1; SMN2ITGB2 | |
| SCHEMBL631494 | 0.83 | F2 (0.48) | SOS1MAPTSMN1; SMN2DPP4KRAS | |
| SCHEMBL13206992 | 0.81 | ITGB2 (0.46) | ITGB2ICAM1ITGAL | |
| SCHEMBL630918 | 0.79 | FKBP1A (0.45) | SOS1MAPTITGB2ICAM1ITGAL | |
| SCHEMBL630182 | 0.73 | LMNA (0.44) | ALDH1A1MAPTSMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL1384829 | 0.72 | KMT2A (0.50) | ALDH1A1MAPTSMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL1383977 | 0.72 | KMT2A (0.50) | ALDH1A1MAPTSMN1; SMN2ITGB2ICAM1 | |
| SCHEMBL1385938 | 0.70 | F2 (0.51) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL1380411 | 0.70 | F2 (0.51) | MAPTSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778637-B1 | FKBP-binding composition and pharmaceutical use thereof | AVENTIS PHARMA INC (US) | 2012-02-22 | — | — | EP | claimed |