Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6306255

C1=CC([Hf+2]2(C3C=Cc4ccccc43)CCCC2)c2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 1/20 0.33
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7629694 0.92 HTR2A (0.35) HTR6HTR2ACYP2D6
Hydrochloric Acid SCHEMBL818678 0.92 HTR2A (0.35) HTR6HTR2ACYP2D6
Fluoride Ion SCHEMBL1131041 0.89 HTR2A (0.35) HTR6HTR2ACYP2D6
Bromide SCHEMBL3998078 0.89 HTR2A (0.39) HTR6HTR2ACYP2D6
Hydrochloric Acid SCHEMBL8589431 0.79
Hydrochloric Acid SCHEMBL9700320 0.77 CYP2D6 (0.31) HTR6HTR2ACYP2D6
Hydrochloric Acid SCHEMBL9220718 0.73 SIGMAR1 (0.33) HTR6HTR2ACYP2D6
Hydrochloric Acid SCHEMBL7926821 0.70 HTR2A (0.33) HTR6HTR2ACYP2D6
Hydrochloric Acid SCHEMBL4467645 0.70 HTR2A (0.33) HTR6HTR2ACYP2D6
Hydrochloric Acid SCHEMBL2778636 0.68 CHRNB2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6897261-B1 Branched olefinic macromonomer, olefin graft copolymer, and olefin resin composition IDEMITSU KOSAN CO., LTD. (JP) 2005-05-24 US disclosed
EP-1209173-A1 BRANCHED OLEFINIC MACROMONOMER, OLEFIN GRAFT COPOLYMER, AND OLEFIN RESIN COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-05-29 EP disclosed