Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7629694 | 0.80 | HTR2A (0.35) | CYP2D6HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL818678 | 0.80 | HTR2A (0.35) | CYP2D6HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6306255 | 0.77 | HTR6 (0.33) | CYP2D6HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL4467645 | 0.77 | HTR2A (0.33) | CYP2D6HTR6HTR2A | |
| Fluoride Ion SCHEMBL1131041 | 0.77 | HTR2A (0.35) | CYP2D6HTR6HTR2A | |
| Bromide SCHEMBL3998078 | 0.77 | HTR2A (0.39) | CYP2D6HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL9220718 | 0.72 | SIGMAR1 (0.33) | CYP2D6HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL7926821 | 0.70 | HTR2A (0.33) | CYP2D6HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL8589431 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL4467577 | 0.65 | HTR2A (0.34) | CYP2D6HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086134-A | Coordination catalyst containing metallocene and aluminoxane compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |