Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7629694 | 1.00 | HTR2A (0.35) | HTR2AHTR6CYP2D6 | |
| Fluoride Ion SCHEMBL1131041 | 0.96 | HTR2A (0.35) | HTR2AHTR6CYP2D6 | |
| Bromide SCHEMBL3998078 | 0.96 | HTR2A (0.39) | HTR2AHTR6CYP2D6 | |
| Hydrochloric Acid SCHEMBL6306255 | 0.92 | HTR6 (0.33) | HTR2AHTR6CYP2D6 | |
| Hydrochloric Acid SCHEMBL8589431 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL9700320 | 0.80 | CYP2D6 (0.31) | HTR2AHTR6CYP2D6 | |
| Hydrochloric Acid SCHEMBL9220718 | 0.76 | SIGMAR1 (0.33) | HTR2AHTR6CYP2D6 | |
| Hydrochloric Acid SCHEMBL2778842 | 0.74 | CHRNB2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL2778636 | 0.74 | CHRNB2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4467645 | 0.73 | HTR2A (0.33) | HTR2AHTR6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592403-B2 | Ethylene polymer, preparation process thereof and molded articles of the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-22 | — | — | US | claimed |
| US-20070293640-A1 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-12-20 | — | — | US | claimed |
| US-7223822-B2 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-29 | — | — | US | claimed |
| US-20040220359-A1 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-04 | — | — | US | claimed |
| WO-2004058686-A1 | HYDROXYPROPYL AMIDES FOR THE TREATMENT OF ALZHEIMER’S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2004-07-15 | — | — | WO | claimed |
| EP-0294942-B2 | Solid catalyst for polymerizing an olefin | MITSUI CHEMICALS INC (JP) | 2002-05-08 | — | — | EP | claimed |
| US-6127305-A | Catalyst and process for polymerizing alpha-olefins | ENICHEM S.P.A (IT) | 2000-10-03 | — | — | US | claimed |
| EP-0615981-B1 | Supported catalyst system, its preparation and its use in olefin polymerisation | TARGOR GMBH (DE) | 1998-05-06 | — | — | EP | claimed |
| US-5714426-A | COORDINATION CATALYST COMPRISING AN ETHYLENEBIS(INDENYL)HAFNIUM AND AN ALUMINUM COMPOUND OR ALUMOXANE; ETHYLENE COPOLYMERS HAVING EXCELLENT FLOWABILITY AND NARROW MOLECULAR WEIGHT DISTRIBUTION; PACKAGING FILMS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-03 | — | — | US | claimed |
| US-5708090-A | Process for the preparation of a polypropylene molding composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | claimed |
| EP-0610852-B1 | Process for preparing cyclo-olefin polymers | HOECHST AG (DE) | 1997-05-07 | — | — | EP | claimed |
| US-5545829-A | Process for preparing cycloolefin copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | claimed |
| EP-0708117-A1 | Process for producing copolymer rubber | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | claimed |
| EP-0294942-B1 | Solid catalyst for polymerizing an olefin | MITSUI PETROCHEMICAL IND (JP) | 1994-07-13 | — | — | EP | claimed |
| EP-0366290-B1 | Process for producing olefin polymers | CHISSO CORP (JP) | 1994-06-29 | — | — | EP | claimed |
| US-5322902-A | Process for the preparation of a polypropylene molding composition | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-21 | — | — | US | claimed |
| EP-0588404-A2 | Catalyst and process for polymerizing alpha-olefins | ENICHEM S.p.A. (IT) | 1994-03-23 | — | — | EP | claimed |
| US-5280074-A | Process for the preparation of a polypropylene molding composition | HOECHST AG (DE) | 1994-01-18 | — | — | US | claimed |
| EP-0384263-B1 | PROCESS FOR PREPARING A STATISTICAL PROPYLENE COPOLYMER | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | claimed |
| EP-0366290-A2 | Process for producing olefin polymers | CHISSO CORPORATION (JP) | 1990-05-02 | — | — | EP | claimed |