SCHEMBL6307073

SCHEMBL6307073

Ic1cccc(-c2cc(I)ccc2-c2ccccc2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 2/20 0.38
BACE1 P56817 1/20 0.38
METAP2 P50579 1/20 0.38
ALOX5 P09917 1/20 0.38
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
ALDH1A1 P00352 5/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
NR2F2 P24468 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ESR2 Q92731 1/20 0.34
GALR1 P47211 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
HSD17B10 Q99714 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24658105 1.00 PDE4A (0.38) PDE4ABACE1METAP2ALOX5CHRNB4
SCHEMBL13445421 0.91 BACE1 (0.44) BACE1ALOX5ALDH1A1ESR2HSD17B10
SCHEMBL19607480 0.89 BACE1 (0.42) PDE4ABACE1METAP2ALOX5CHRNB4
SCHEMBL20081051 0.88 MEN1 (0.44) PDE4ABACE1METAP2ALOX5CHRNB4
SCHEMBL18969769 0.88 LMNA (0.42) PDE4ABACE1METAP2ALOX5CHRNB4
SCHEMBL6307069 0.87 BACE1 (0.41) BACE1ALOX5ALDH1A1LMNAMAPT
SCHEMBL7714897 0.87 BACE1 (0.41) PDE4ABACE1METAP2ALOX5CHRNB4
SCHEMBL1032857 0.87 BACE1 (0.41) BACE1ALOX5ALDH1A1LMNAMAPT
SCHEMBL16947236 0.85 NPC1 (0.42) ALDH1A1MAPTHTTSMN1; SMN2TDP1
SCHEMBL24656818 0.85 CNR2 (0.45) SMN1; SMN2ESR2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107963972-B Organic electroluminescent device 保土谷化学工业株式会社 2021-09-03 CN disclosed
EP-3220437-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2021-04-14 EP disclosed
EP-3244462-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2020-11-11 EP disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
EP-2960958-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2018-10-31 EP disclosed
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2018-01-04 US disclosed
EP-3244462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3220437-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-09-20 EP disclosed
US-20160126464-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 US disclosed
US-20150380657-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2015-12-31 US disclosed
EP-2960958-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2015-12-30 EP disclosed
US-9048435-B2 Organic semiconducting materials and organic component NOVALED AG (DE) 2015-06-02 US disclosed
US-20120223296-A1 Organic Semiconducting Materials and Organic Component SENSIENT IMAGING TECHNOLOGIES GMBH (DE) 2012-09-06 US disclosed
US-6936679-B2 Charge-transporting polymer FUJI XEROX CO., LTD. (JP) 2005-08-30 US disclosed
US-20030207187-A1 Charge-transporting polymer FUJI XEROX CO., LTD. (JP) 2003-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 PDE4A 4359/4885BACE1 3680/4885METAP2 4349/4885
US-20180006235-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC18A1, KCNH1 PDE4A 4359/4885BACE1 3680/4885METAP2 4349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.