Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181005 | 0.97 | TSHR (0.56) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13198785 | 0.94 | ALDH1A1 (0.58) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL27539023 | 0.94 | TSHR (0.54) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL909586 | 0.94 | TSHR (0.54) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| Acetonitrile SCHEMBL28159901 | 0.90 | ALDH1A1 (0.55) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28381532 | 0.87 | ALDH1A1 (0.49) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9447402 | 0.84 | ALDH1A1 (0.54) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5164828 | 0.84 | L3MBTL1 (0.56) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5773518 | 0.84 | ALDH1A1 (0.50) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5052368 | 0.84 | ALDH1A1 (0.74) | TSHRTRPA1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972270-B2 | Catalyst modifiers and their use in the polymerization of olefin(s) | UNIVATION TECHNOLOGIES, LLC (US) | 2005-12-06 | — | — | US | disclosed |
| US-6960549-B2 | Catalyst modifiers and their use in the polymerization of olefin(s) | UNIVATION TECHNOLOGIES, LLC (US) | 2005-11-01 | — | — | US | disclosed |
| CN-1160383-C | Catalyst modifiers and their use in olefin polymerization | �������ٶ������������ι�˾ | 2004-08-04 | — | — | CN | disclosed |
| US-20030207753-A1 | One acid and at least one base and/or at least one reductant and at least one oxidant that when used with a polymerization catalyst in a polymerization process results in the controllable generation of a catalyst inhibitor that renders | WENZEL TIMOTHY T (US) | 2003-11-06 | — | — | US | disclosed |
| CN-1374974-A | Catalyst modifiers and their use in the polymerization of olefin(s) | UNIVATION TECH LLC (US) | 2002-10-16 | — | — | CN | disclosed |
| US-6346584-B1 | PROCESS FOR POLYMERIZING OLEFIN(S) IN PRESENCE OF POLYMERIZATION CATALYST AND AT LEAST TWO DIFFERENT COMPOUNDS WHICH REACT AT TEMPERATURE ABOVE OPERATING TEMPERATURE TO FORM CATALYST INHIBITOR THAT REDUCES EFFECTIVENESS OF CATALYST | UNIVATION TECHNOLOGIES, LLC | 2002-02-12 | — | — | US | disclosed |
| US-20020013219-A1 | Catalyst modifiers and their use in the polymerization of olefin(s) | WENZEL TIMOTHY T (US) | 2002-01-31 | — | — | US | disclosed |
| EP-1159312-A2 | CATALYST MODIFIERS AND THEIR USE IN THE POLYMERIZATION OF OLEFIN(S) | Univation Technologies LLC (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000035969-A2 | CATALYST MODIFIERS AND THEIR USE IN THE POLYMERIZATION OF OLEFIN(S) | UNIVATION TECHNOLOGIES, LLC (US) | 2000-06-22 | — | — | WO | disclosed |
| EP-0178947-B1 | 1-[(Aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-alpha,alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4812452-A | ANTIARRHYTHMIA AGENTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-14 | — | — | US | disclosed |
| US-4812451-A | ANTIARRHYTHMIA AGENTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-14 | — | — | US | disclosed |
| US-4810703-A | ANTIARRHYTHMIA | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| US-4594343-A | FOR DEEP FAT FRYING VAT OIL; REMOVING CONTAMINANTS; RESTAURANTS | A.H. ROBINS COMPANY, INCORPORATED, A DE CORP. | 1986-06-10 | — | — | US | disclosed |
| EP-0178947-A2 | 1-[(Aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-alpha,alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-04-23 | — | — | EP | disclosed |