Sugi Predict

Sugi Predict / Compounds / SCHEMBL6308565

SCHEMBL6308565

SCHEMBL6308565

O=S(=O)(F)c1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.59
▸ CA2 P00918 7/20 0.56
▸ CA1 P00915 5/20 0.56
▸ CA12 O43570 3/20 0.56
▸ CA9 Q16790 3/20 0.56
▸ ENPP2 Q13822 1/20 0.56
▸ F2 P00734 2/20 0.46
▸ TMPRSS4 Q9NRS4 2/20 0.46
▸ TP53 P04637 2/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ GAA P10253 1/20 0.45
▸ PKM P14618 1/20 0.45
▸ CA7 P43166 1/20 0.45
▸ ALDH1A1 P00352 2/20 0.44
▸ CYP3A4 P08684 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ ALOX15 P16050 2/20 0.44
▸ RECQL P46063 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11574176 0.85 TSHR (0.56) LMNACA2CA1CA12CA9
Hydroquinone SCHEMBL32682314 0.82 CA2 (0.57) LMNACA2CA1CA12CA9
SCHEMBL29724901 0.77 GAA (0.67) LMNACA2CA1CA12CA9
SCHEMBL3792342 0.77 GAA (0.67) LMNACA2CA1CA12CA9
SCHEMBL547730 0.77 LMNA (0.65) LMNACA2CA1CA12CA9
SCHEMBL8028971 0.77 LMNA (0.65) LMNACA2CA1CA12CA9
SCHEMBL11573848 0.77 CA12 (0.52) LMNACA2CA1CA12CA9
SCHEMBL10454823 0.77 CA2 (0.50) LMNACA2CA1CA12CA9
SCHEMBL18838 0.77 GAA (0.67) LMNACA2CA1CA12CA9
SCHEMBL124022 0.77 GAA (0.67) LMNACA2CA1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5759211-A COLORING SYNTHETIC TEXTILE OR FIBER BLEND ZENECA LIMITED (GB) 1998-06-02 — — US claimed
US-12630566-B2 KRas G12D inhibitors Mirati Therapeutics, Inc. (US) 2026-05-19 — — US disclosed
US-20240309020-A1 KRAS G12D INHIBITORS ARRAY BIOPHARMA INC. 2024-09-19 — — US disclosed
CN-111689929-B Sulfur fluoride (VI) compound and preparation method thereof 斯克里普斯研究所 2024-05-31 — — CN disclosed
US-11964989-B2 KRas G12D inhibitors Mirati Therapeutics, Inc. (US) 2024-04-23 — — US disclosed
CN-114615981-B KRAS G12D inhibitors 米拉蒂治疗股份有限公司 2024-04-12 — — CN disclosed
EP-4295841-A2 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION The Scripps Research Institute (US) 2023-12-27 — — EP disclosed
US-20230341777-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING TERMINAL-BLOCKED REACTION PRODUCT NISSAN CHEMICAL CORPORATION (JP) 2023-10-26 — — US disclosed
US-20230341777-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING TERMINAL-BLOCKED REACTION PRODUCT NISSAN CHEMICAL CORPORATION (JP) 2023-10-26 — — US disclosed
US-20230296984-A1 EUV RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-09-21 — — US disclosed
US-20050137172-A1 Haloacetamide and azide substituted compounds and methods of use thereof DALTON JAMES T (US) 2005-06-23 — — US disclosed
WO-2005037206-A2 ANTI-CANCER COMPOUNDS AND METHODS OF USE THEREOF GTX, INC. (US) 2005-04-28 — — WO disclosed
WO-2005037205-A2 HALOACETAMIDE AND AZIDE SUBSTITUTED COMPOUNDS AND METHODS OF USE THEREOF UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-04-28 — — WO disclosed
US-20050085449-A1 Haloacetamide and azide substituted compounds and methods of use thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-04-21 — — US disclosed
US-5759211-A COLORING SYNTHETIC TEXTILE OR FIBER BLEND ZENECA LIMITED (GB) 1998-06-02 — — US disclosed
EP-0743994-A1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1996-11-27 — — EP disclosed
WO-1995021958-A1 ANTHRAQUINONE DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF ZENECA LIMITED (GB) 1995-08-17 — — WO disclosed
US-4554381-A BORON TRIFLUORIDE, HYDROFLUORIC ACID RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-11-19 — — US disclosed
US-4552984-A SULFONYLATION IN PRESENCE OF BORON TRIFLUORIDE, HYDROGEN FLUORIDE RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-11-12 — — US disclosed
US-3808010-A SURFACE-COATING COMPOSITIONS KAY-FRIES, INC. 1974-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085449-A1 Haloacetamide and azide substituted compounds and methods of use thereof CASP3, MGMT, BCL2 LMNA 2911/4885CA2 89/4885CA1 65/4885
US-20050137172-A1 Haloacetamide and azide substituted compounds and methods of use thereof CASP3, MGMT, BCL2 LMNA 2911/4885CA2 89/4885CA1 65/4885
US-12630566-B2 KRas G12D inhibitors KRAS, NRAS, HRAS LMNA 4684/4885CA2 730/4885CA1 2449/4885
US-11964989-B2 KRas G12D inhibitors KRAS, NRAS, HRAS LMNA 3814/4885CA2 1277/4885CA1 2753/4885
US-20240309020-A1 KRAS G12D INHIBITORS KRAS, NRAS, HRAS LMNA 4069/4885CA2 1714/4885CA1 3229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.