SCHEMBL6310060

SCHEMBL6310060

Oc1cccc(-c2csc(Nc3ccc(F)cc3F)n2)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.64
CTRC Q99895 1/20 0.64
AGER Q15109 2/20 0.57
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
MAPT P10636 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MAPK1 P28482 1/20 0.47
RECQL P46063 1/20 0.47
VCP P55072 1/20 0.47
AGTR1 P30556 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
ROCK1 Q13464 1/20 0.45
PSMD14 O00487 1/20 0.44
AMY1A P0DUB6 1/20 0.42
CYP1A1 P04798 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP1B1 Q16678 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19851003 0.82 CTRB1 (0.64) CTRB1CTRCAGERMEN1KMT2A
SCHEMBL19851002 0.77 MEN1 (0.70) CTRB1CTRCMEN1KMT2ANPC1
SCHEMBL28712020 0.74 CYP1A1 (0.68) CTRB1CTRCAGERMEN1KMT2A
SCHEMBL16603960 0.72 AGER (1.00) AGERMEN1KMT2ANPC1RAB9A
SCHEMBL19839869 0.72 RAB9A (0.70) CTRB1CTRCMEN1KMT2ANPC1
SCHEMBL29276772 0.69 AGER (0.75) AGERMEN1KMT2ANPC1RAB9A
SCHEMBL19851004 0.69 AGER (0.70) AGERMEN1KMT2ANPC1RAB9A
SCHEMBL23742582 0.69 CYP1A1 (0.57) CTRB1CTRCMEN1KMT2AMAPT
SCHEMBL6310064 0.68 CTRB1 (0.50) CTRB1CTRCAGERMEN1KMT2A
SCHEMBL29276768 0.67 NPY5R (0.66) AGERMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6887658-B2 Methods of identifying non-specific inhibitors of biomolecules NORTHWESTERN UNIVERSITY (US) 2005-05-03 US disclosed
US-20040234942-A1 METHODS OF IDENTIFYING NON-SPECIFIC INHIBITORS OF BIOMOLECULES NORTHWESTERN UNIVERSITY 2004-11-25 US disclosed