Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301912 | 0.84 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL14633632 | 0.84 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7776355 | 0.82 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4588400 | 0.82 | KMT2A (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL16573282 | 0.81 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL147358 | 0.81 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL16470335 | 0.80 | KMT2A (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL10974048 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL27499998 | 0.79 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6297678 | 0.79 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967205-B1 | Compounds with antibacterial and antiparasitic properties | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-11-22 | — | — | US | disclosed |