Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685962 | 0.75 | CLK4 (0.64) | CLK4ADRB2AOC3CYP2A6NPC1 | |
| SCHEMBL6226582 | 0.73 | CLK4 (0.44) | CLK4ADRB2AOC3CYP2A6NPC1 | |
| SCHEMBL1124023 | 0.72 | ALDH1A1 (0.52) | CLK4ADRB2CYP2A6SMN1; SMN2 | |
| SCHEMBL6870760 | 0.72 | CLK4 (0.47) | CLK4ADRB2AOC3CYP2A6NPC1 | |
| SCHEMBL16625771 | 0.72 | CLK4 (0.61) | CLK4ADRB2AOC3CYP2A6NPC1 | |
| SCHEMBL6850715 | 0.69 | CLK4 (0.40) | CLK4ADRB2AOC3CYP2A6NPC1 | |
| SCHEMBL6850718 | 0.69 | CLK4 (0.40) | CLK4ADRB2AOC3CYP2A6NPC1 | |
| SCHEMBL12428996 | 0.69 | CLK4 (0.52) | CLK4ADRB2AOC3CYP2A6NPC1 | |
| SCHEMBL2258014 | 0.69 | CLK4 (0.52) | CLK4ADRB2AOC3CYP2A6NPC1 | |
| SCHEMBL10648374 | 0.68 | KDM4E (0.44) | CLK4ADRB2AOC3CYP2A6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250713-A1 | 11,12-Cyclic thiocarbamate macrolide antibacterial agents | ZHU BIN | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250713-A1 | 11,12-Cyclic thiocarbamate macrolide antibacterial agents | MRPL21, TTC14, MRPL12 | CLK4 3828/4885ADRB2 4761/4885AOC3 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.