Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20138438 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2LMNACLK4 | |
| SCHEMBL11823541 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2LMNACYP2A6 | |
| SCHEMBL6685962 | 0.80 | CLK4 (0.64) | ALDH1A1KDM4ESMN1; SMN2LMNACLK4 | |
| SCHEMBL5799192 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2LMNACLK4 | |
| SCHEMBL5799195 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2LMNACLK4 | |
| SCHEMBL23637787 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2CYP2A6HSD17B10 | |
| SCHEMBL6870760 | 0.77 | CLK4 (0.47) | ALDH1A1KDM4ESMN1; SMN2CLK4ADRB2 | |
| SCHEMBL16625771 | 0.77 | CLK4 (0.61) | ALDH1A1KDM4ESMN1; SMN2LMNACLK4 | |
| SCHEMBL1030215 | 0.77 | HSD17B10 (0.52) | ALDH1A1KDM4ESMN1; SMN2CYP2A6HSD17B10 | |
| SCHEMBL7780699 | 0.77 | ALDH5A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2LMNACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761452-A | Method for preparing hollow covalent organic framework material | 浙江大学 | 2022-07-15 | — | — | CN | claimed |
| CN-113845646-A | Dual-functionalized conjugated microporous polymer based on pyrimidine and cyano, and preparation method and application thereof | 浙江时间新材料有限公司 | 2021-12-28 | — | — | CN | claimed |
| CN-112898544-A | Difunctional conjugated microporous polymer containing pyrimidine ring and cyano and preparation method thereof | 台州学院 | 2021-06-04 | — | — | CN | claimed |
| CN-112574395-A | Conjugated microporous polymer based on 2,4, 6-tri (4-formylphenyl) pyrimidine and preparation method thereof | 台州学院 | 2021-03-30 | — | — | CN | claimed |
| CN-111848891-A | Covalent organic polymer based on 2,4, 6-tri (4-formylphenyl) pyrimidine and preparation method thereof | 台州学院 | 2020-10-30 | — | — | CN | claimed |
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-11857550-B2 | Benzathine analogs | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2024-01-02 | — | — | US | disclosed |
| WO-2023065714-A1 | PYRIMIDINE- AND CYANO GROUP-BASED BIFUNCTIONAL CONJUGATED MICROPOROUS POLYMER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 浙江时间新材料有限公司 | 2023-04-27 | — | — | WO | disclosed |
| US-11459321-B2 | Broad spectrum antiviral compositions and methods | EVRYS BIO, LLC (US) | 2022-10-04 | — | — | US | disclosed |
| CN-114761452-A | Method for preparing hollow covalent organic framework material | 浙江大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-113845646-A | Dual-functionalized conjugated microporous polymer based on pyrimidine and cyano, and preparation method and application thereof | 浙江时间新材料有限公司 | 2021-12-28 | — | — | CN | disclosed |
| US-20210315895-A1 | BENZATHINE ANALOGS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-10-14 | — | — | US | disclosed |
| US-6288120-B1 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |
| WO-2001016131-A2 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD (CH) | 2001-03-08 | — | — | WO | disclosed |
| EP-1021410-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| EP-1000619-A2 | Method for treating glaucoma | Pfizer Products Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0946501-A1 | PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS | PFIZER INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1999019300-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1998028264-A1 | PREVENTION OF LOSS AND RESTORATION OF BONE MASS BY CERTAIN PROSTAGLANDIN AGONISTS | PFIZER INC. (US) | 1998-07-02 | — | — | WO | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | ALDH1A1 290/4885KDM4E 3207/4885SMN1; SMN2 281/4885 |
| US-11459321-B2 | Broad spectrum antiviral compositions and methods | IRF3, MAVS, ZC3HAV1 | ALDH1A1 2639/4885KDM4E 2307/4885SMN1; SMN2 259/4885 |
| US-11857550-B2 | Benzathine analogs | HDAC10, CFTR, HBB | ALDH1A1 2621/4885KDM4E 1728/4885SMN1; SMN2 3018/4885 |
| US-20210315895-A1 | BENZATHINE ANALOGS | HDAC10, CFTR, HBB | ALDH1A1 2621/4885KDM4E 1728/4885SMN1; SMN2 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.