Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30058880 | 0.89 | ALDH1A1 (0.53) | SMN1; SMN2KMT2APDE5AALDH1A1KDM4E | |
| SCHEMBL6310452 | 0.86 | NPC1 (0.60) | SMN1; SMN2KMT2APDE5AALDH1A1KDM4E | |
| SCHEMBL2766185 | 0.81 | HPGD (0.64) | SMN1; SMN2KMT2APDE5AALDH1A1KDM4E | |
| SCHEMBL7055631 | 0.80 | HSD17B10 (0.57) | SMN1; SMN2KMT2APDE5AALDH1A1KDM4E | |
| SCHEMBL6970367 | 0.80 | L3MBTL1 (0.55) | SMN1; SMN2KMT2APDE5AALDH1A1KDM4E | |
| SCHEMBL6313414 | 0.77 | LMNA (0.72) | SMN1; SMN2KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL24770658 | 0.75 | MAPK1 (0.62) | SMN1; SMN2KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL8478547 | 0.74 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2APDE5AALDH1A1KDM4E | |
| SCHEMBL307301 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL6975573 | 0.73 | ACHE (0.67) | SMN1; SMN2KMT2APDE5AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | MITSUI CHEMICALS, INC. (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1489073-A1 | PROCESS FORPREPARATION OF ALKOXYBENZAMIDES AND THIAZOLYL ISOCYANATES | MITSUI CHEMICALS, INC. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143581-A1 | Process for preparation of alkoxybenzamides and thiazolyl isocyanates | CBR3, CBR1, IDH1 | SMN1; SMN2 4217/4885KMT2A 613/4885PDE5A 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.