Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316387 | 0.85 | LMNA (0.45) | RAB9ANPC1TP53RECQLSMN1; SMN2 | |
| SCHEMBL6310298 | 0.81 | MAPT (0.48) | RAB9ANPC1MAPTALDH1A1LMNA | |
| SCHEMBL5829259 | 0.80 | L3MBTL1 (0.45) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6308253 | 0.80 | ALOX15 (0.50) | NPC1ADRB3ADRB1KCNA5MAPT | |
| SCHEMBL3068944 | 0.77 | RAB9A (0.45) | RAB9ANPC1TP53RECQLSMN1; SMN2 | |
| SCHEMBL5929602 | 0.76 | KCNA5 (0.57) | SMN1; SMN2ADRB3ADRB1KCNA5ALDH1A1 | |
| SCHEMBL5929610 | 0.76 | KCNA5 (0.57) | SMN1; SMN2ADRB3ADRB1KCNA5ALDH1A1 | |
| SCHEMBL3103596 | 0.76 | RAB9A (0.47) | RAB9ANPC1TP53RECQLSMN1; SMN2 | |
| SCHEMBL6310768 | 0.76 | NPY5R (0.49) | RAB9ANPC1TP53RECQLSMN1; SMN2 | |
| SCHEMBL3067372 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2ADRB3ADRB1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123727-A1 | 3-ARYL-3-HYDROXY- AND 3-ARYL-3-OXOPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | ATP CAPITAL LP | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | CYP21A2, HAO1, AHR | RAB9A 2019/4885NPC1 1995/4885TP53 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.