Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.48 |
| ▸ | ITGAV | P06756 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459275 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2TBXAS1NAPRTCFTRSLC6A2 | |
| SCHEMBL17183618 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2TBXAS1NAPRTCFTRSLC6A2 | |
| SCHEMBL27956700 | 0.84 | L3MBTL1 (0.49) | SMN1; SMN2TBXAS1CFTRSLC6A2SLC6A4 | |
| SCHEMBL5856512 | 0.84 | TBXAS1 (0.53) | SMN1; SMN2TBXAS1NAPRTCFTRSLC6A2 | |
| SCHEMBL27965757 | 0.83 | TBXAS1 (0.60) | SMN1; SMN2TBXAS1NAPRTCFTRSLC6A2 | |
| SCHEMBL30082780 | 0.83 | TBXAS1 (0.60) | SMN1; SMN2TBXAS1NAPRTCFTRSLC6A2 | |
| SCHEMBL27965558 | 0.83 | TBXAS1 (0.60) | SMN1; SMN2TBXAS1NAPRTCFTRSLC6A2 | |
| SCHEMBL2638943 | 0.83 | TBXAS1 (0.60) | SMN1; SMN2TBXAS1NAPRTCFTRSLC6A2 | |
| SCHEMBL11990053 | 0.82 | TBXAS1 (0.63) | SMN1; SMN2TBXAS1NAPRTCFTRSLC6A2 | |
| SCHEMBL2570051 | 0.81 | TBXAS1 (0.67) | SMN1; SMN2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405917-B1 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | SALTIGO GMBH (DE) | 2013-08-14 | — | — | EP | claimed |
| CN-101909451-A | Fungicidal mixtures II | BASF SE | 2010-12-08 | — | — | CN | disclosed |
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | disclosed |
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | disclosed |
| EP-2222169-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-2222169-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009063075-A3 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2010-05-06 | — | — | WO | disclosed |
| US-7553970-B2 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2009-06-30 | — | — | US | disclosed |
| WO-2009063075-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009063075-A2 | FUNGICIDAL MIXTURES II | BASF SE (DE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2005123727-A1 | 3-ARYL-3-HYDROXY- AND 3-ARYL-3-OXOPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | ATP CAPITAL LP | 2005-12-15 | — | — | US | disclosed |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | CYP21A2, HAO1, AHR | SMN1; SMN2 2798/4885TBXAS1 3684/4885NAPRT 2922/4885 |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | HPD, HAAO, GRHPR | SMN1; SMN2 4276/4885TBXAS1 796/4885NAPRT 1270/4885 |
| US-20100267555-A1 | Fungicidal mixtures II | CBR3, CBR1, NOX3 | SMN1; SMN2 3685/4885TBXAS1 780/4885NAPRT 2488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.