Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1155730 | 0.85 | FAAH (0.55) | LMNAFAAHL3MBTL1CES2CES1 | |
| SCHEMBL800064 | 0.78 | EPHX2 (0.56) | LMNAFAAHL3MBTL1CES2CES1 | |
| SCHEMBL4656202 | 0.78 | ALDH1A1 (0.56) | LMNAFAAHL3MBTL1CES2CES1 | |
| SCHEMBL163232 | 0.77 | EPHX2 (0.59) | FAAHL3MBTL1CES2CES1AKR1B1 | |
| SCHEMBL25813103 | 0.76 | L3MBTL1 (0.47) | LMNAFAAHL3MBTL1CES2CES1 | |
| SCHEMBL2299970 | 0.76 | ALDH1A1 (0.50) | LMNAL3MBTL1KMT2AALDH1A1HPGD | |
| SCHEMBL26255812 | 0.76 | ALDH1A1 (0.50) | LMNAL3MBTL1KMT2AALDH1A1HPGD | |
| SCHEMBL2299968 | 0.76 | ALDH1A1 (0.50) | LMNAL3MBTL1KMT2AALDH1A1HPGD | |
| SCHEMBL8171037 | 0.76 | ALDH1A1 (0.50) | LMNAL3MBTL1KMT2AALDH1A1HPGD | |
| SCHEMBL18806518 | 0.76 | ALDH1A1 (0.50) | LMNAL3MBTL1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | LMNA 3993/4885FAAH 4836/4885L3MBTL1 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.