Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390509 | 0.77 | EGFR (0.33) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL4559535 | 0.76 | CASP1 (0.38) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL21511943 | 0.76 | APP (0.35) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| Hydrochloric Acid SCHEMBL6312425 | 0.75 | POLB (0.39) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL21512315 | 0.74 | CA12 (0.33) | APPADRA2AADRA2BADRA2CEGFR | |
| SCHEMBL30724396 | 0.71 | TDP1 (0.46) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL13548437 | 0.71 | TDP1 (0.46) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL6311659 | 0.70 | ALDH1A1 (0.38) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL6311663 | 0.70 | ALDH1A1 (0.38) | ALDH1A1CYP3A4THRBALOX15RECQL | |
| SCHEMBL19372385 | 0.70 | MAPT (0.38) | ALDH1A1TDP1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849766-B2 | 1,4-diamino-2-alkenylbenzene derivatives, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20030121110-A1 | Novel 1,4-diamino-2-alkenylbenzene derivatives , and dyes containing these compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030121110-A1 | Novel 1,4-diamino-2-alkenylbenzene derivatives , and dyes containing these compounds | AOC1, AOX1, GPX1 | ALDH1A1 5/4885CYP3A4 441/4885THRB 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.