Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 7/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.51 |
| ▸ | PARK7 | Q99497 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP4 | P49662 | 1/20 | 0.48 |
| ▸ | CASP9 | P55211 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15215078 | 0.85 | ALDH1A1 (0.71) | ALDH1A1ALDH2ALDH3A1CHRM5CA12 | |
| SCHEMBL6285415 | 0.83 | DRD2 (0.62) | ALDH1A1ALDH2ALDH3A1CHRM5 | |
| SCHEMBL15215070 | 0.81 | ALDH1A1 (0.70) | ALDH1A1ALDH2ALDH3A1CHRM5PARK7 | |
| SCHEMBL15215034 | 0.74 | ALDH1A1 (0.67) | ALDH1A1ALDH2ALDH3A1CHRM5PARK7 | |
| SCHEMBL15206575 | 0.74 | CHRM5 (0.66) | ALDH1A1ALDH2ALDH3A1CHRM5CA12 | |
| SCHEMBL15215074 | 0.73 | ALDH1A1 (0.62) | ALDH1A1ALDH2ALDH3A1CHRM5PARK7 | |
| SCHEMBL15215041 | 0.72 | PARK7 (0.59) | ALDH1A1ALDH2ALDH3A1CHRM5PARK7 | |
| SCHEMBL9053218 | 0.71 | MAOB (0.63) | ALDH1A1ALDH2ALDH3A1BCHE | |
| SCHEMBL27941794 | 0.71 | ALDH3A1 (0.81) | ALDH1A1ALDH2ALDH3A1CHRM5PARK7 | |
| SCHEMBL9062737 | 0.71 | MAOB (0.64) | CES1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906090-B1 | Compositions and methods for treating mycobacterial diseases | ASTRAZENECA AB (SE) | 2005-06-14 | — | — | US | disclosed |