Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.39 |
| ▸ | CTSL | P07711 | 7/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.38 |
| ▸ | ITGAV | P06756 | 5/20 | 0.38 |
| ▸ | CTSB | P07858 | 6/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312633 | 0.75 | MEN1 (0.60) | — | |
| SCHEMBL6310328 | 0.69 | NPSR1 (0.44) | — | |
| SCHEMBL28832879 | 0.65 | SIRT2 (0.56) | CTSSCTSLITGB3CTSBCTSK | |
| SCHEMBL265783 | 0.65 | CTSK (0.66) | CTSSCTSLCTSBCTSKSIRT2 | |
| SCHEMBL329038 | 0.65 | CTSK (0.66) | CTSSCTSLCTSBCTSKSIRT2 | |
| SCHEMBL265461 | 0.65 | CTSK (0.66) | CTSSCTSLCTSBCTSKSIRT2 | |
| Hydrochloric Acid SCHEMBL1161917 | 0.64 | SIRT2 (0.55) | CTSSCTSLITGB3CTSBCTSK | |
| SCHEMBL4828679 | 0.64 | CTSL (0.62) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL28723295 | 0.64 | CTSL (0.62) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL18063383 | 0.64 | FOLH1 (0.65) | CTSSCTSLITGB3ITGAVCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | CTSS 2938/4885CTSL 2137/4885ITGB3 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.