Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607098 | 0.89 | POLB (0.42) | POLBKDM4E | |
| SCHEMBL28700312 | 0.79 | DRD2 (0.32) | POLBCA12CA1CA9 | |
| SCHEMBL9128937 | 0.78 | THRB (0.37) | POLB | |
| SCHEMBL15332756 | 0.78 | TTR (0.33) | — | |
| SCHEMBL6787211 | 0.78 | — | — | |
| SCHEMBL3242496 | 0.78 | CYP1A2 (0.37) | CA12CA1CA9KDM4EALOX5AP | |
| SCHEMBL1716656 | 0.78 | CA12 (0.33) | POLBCA12CA1CA9KDM4E | |
| SCHEMBL6321917 | 0.77 | ALDH1A1 (0.36) | CA12CA1CA9KDM4E | |
| SCHEMBL5981001 | 0.76 | MAPT (0.42) | CA12CA1CA9ALOX5APFEN1 | |
| SCHEMBL932790 | 0.76 | TSHR (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118439991-B | RBJ small molecule inhibitors | 中国医学科学院基础医学研究所 | 2025-01-28 | — | — | CN | disclosed |
| CN-118439991-A | RBJ small molecule inhibitors | 中国医学科学院基础医学研究所 | 2024-08-06 | — | — | CN | disclosed |
| US-6951876-B2 | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents | PFIZER, INC. (US) | 2005-10-04 | — | — | US | disclosed |
| US-6603008-B1 | Inhibit the biosynthesis of prostaglandins by intervention of the action of the enzyme cyclooxygenase on arachidonic acid | PFIZER INC. | 2003-08-05 | — | — | US | disclosed |
| US-20030144280-A1 | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents | PFIZER INC. (US) | 2003-07-31 | — | — | US | disclosed |
| EP-1104760-B1 | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2003-03-12 | — | — | EP | disclosed |
| EP-1104760-A1 | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents | Pfizer Products Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144280-A1 | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents | PTGS1, PTGS2, SULT2A1 | POLB 4700/4885CA12 3101/4885CA1 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.