Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350515 | 0.86 | — | — | |
| SCHEMBL17225408 | 0.77 | NOS3 (0.44) | NOS3NOS2CES1TAAR1MAP3K14 | |
| SCHEMBL9404977 | 0.77 | — | — | |
| SCHEMBL8936321 | 0.75 | CES1 (0.48) | NOS3NOS2KMT2ACES1TAAR1 | |
| SCHEMBL10196360 | 0.74 | NOS3 (0.41) | NOS3NOS2TAAR1MAP3K14PNMT | |
| SCHEMBL15763737 | 0.73 | NOS3 (0.52) | NOS3NOS2CES1TAAR1MAP3K14 | |
| SCHEMBL3974015 | 0.72 | TSHR (0.38) | NOS3NOS2CES1MAPK1ALDH1A1 | |
| SCHEMBL10159213 | 0.71 | NOS3 (0.39) | NOS3NOS2KMT2ATAAR1MAP3K14 | |
| SCHEMBL10514854 | 0.69 | ALDH1A1 (0.35) | CES1ALDH1A1 | |
| SCHEMBL828997 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260034093-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUMITOMO PHARMA AMERICA, INC. (US) | 2026-02-05 | — | — | US | disclosed |
| EP-4642784-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| US-12185626-B2 | Chemical compounds, optoelectronic elements comprising at least one new chemical compound, and use of new chemical compounds in an optoelectronic element | HELIATEK GMBH (DE) | 2024-12-31 | — | — | US | disclosed |
| EP-3890041-B1 | NEW CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT | HELIATEK GMBH (DE) | 2024-12-04 | — | — | EP | disclosed |
| US-20240358675-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUMITOMO PHARMA AMERICA, INC. (US) | 2024-10-31 | — | — | US | disclosed |
| WO-2024145623-A1 | HETEROCYCLIC AND HETEROARYL COMPOUNDS AS INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| CN-118165002-A | Polycyclic compounds and methods of use thereof | 桑诺维恩药品公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-3252057-B1 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2024-03-27 | — | — | EP | disclosed |
| EP-3880659-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2024-01-03 | — | — | EP | disclosed |
| US-20230165146-A1 | CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT | HELIATEK GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-4332724-A | OXIDATION IN PRESENCE OF COBALT CATALYST | AMERICAN CYANAMID CO. (US) | 1982-06-01 | — | — | US | disclosed |
| US-4332724-A | OXIDATION IN PRESENCE OF COBALT CATALYST | AMERICAN CYANAMID CO. (US) | 1982-06-01 | — | — | US | disclosed |
| US-4332724-A | OXIDATION IN PRESENCE OF COBALT CATALYST | AMERICAN CYANAMID CO. (US) | 1982-06-01 | — | — | US | disclosed |
| US-4254268-A | OXIDIZED BY POTASSIUM PERMANGANATE | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4199510-A | Process for oxidation of 4-amidotetrahydrobenzo [b]-thiophenes to 7-keto derivatives with cobaltic salts | AMERICAN CYANAMID COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4199510-A | Process for oxidation of 4-amidotetrahydrobenzo [b]-thiophenes to 7-keto derivatives with cobaltic salts | AMERICAN CYANAMID COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4154740-A | HERBICIDES, ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4125539-A | CHEMICAL INTERMEDIATES FOR ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4096155-A | ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-06-20 | — | — | US | disclosed |
| US-4075228-A | INTERMEDIATES FOR ANIMAL GROWTH PROMOTERS | AMERICAN CYANAMID COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240358675-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | GRIN2C, NLN, COMT | MAOA 23/4885MAOB 11/4885CYP2A6 533/4885 |
| US-20230165146-A1 | CHEMICAL COMPOUNDS, OPTOELECTRONIC ELEMENTS COMPRISING AT LEAST ONE NEW CHEMICAL COMPOUND, AND USE OF NEW CHEMICAL COMPOUNDS IN AN OPTOELECTRONIC ELEMENT | ETV6, ALK, CHRM3 | MAOA 507/4885MAOB 242/4885CYP2A6 22/4885 |
| US-20260034093-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SLC6A3, SLC6A11, SLC6A13 | MAOA 112/4885MAOB 204/4885CYP2A6 1156/4885 |
| US-12185626-B2 | Chemical compounds, optoelectronic elements comprising at least one new chemical compound, and use of new chemical compounds in an optoelectronic element | ETV6, ALK, CHRM3 | MAOA 507/4885MAOB 242/4885CYP2A6 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.