Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317318 | 0.90 | SIGMAR1 (0.45) | SIGMAR1HTR2AMAPTCCR5POLB | |
| SCHEMBL6104472 | 0.88 | SIGMAR1 (0.50) | SIGMAR1HTR2ACCR5POLBOPRM1 | |
| SCHEMBL6103164 | 0.85 | OPRK1 (0.48) | SIGMAR1HTR2AALDH1A1CCR5POLB | |
| SCHEMBL6309994 | 0.85 | OPRK1 (0.48) | SIGMAR1HTR2AALDH1A1CCR5POLB | |
| SCHEMBL341489 | 0.82 | HTR2A (0.66) | HTR2APOLBOPRM1 | |
| SCHEMBL6104408 | 0.80 | SIGMAR1 (0.47) | SIGMAR1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9995204 | 0.77 | HTR2A (0.51) | SIGMAR1HTR2ACCR5POLBEPHX2 | |
| SCHEMBL6102744 | 0.77 | HTR2A (0.50) | SIGMAR1HTR2ACCR5POLBEPHX2 | |
| SCHEMBL6103397 | 0.77 | CCR5 (0.48) | HTR2AMEN1ALDH1A1KMT2ACCR5 | |
| SCHEMBL4203051 | 0.76 | SIGMAR1 (0.47) | SIGMAR1HTR2AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014757-A1 | Azacyclic compounds | ANDERSSON CARL-MAGNUS A (DK) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014757-A1 | Azacyclic compounds | HTR6, TPMT, HNMT | SIGMAR1 295/4885HTR2A 10/4885MEN1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.