Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370028 | 0.80 | ADORA1 (0.41) | LRRK2CCR1CCR5CCR8PARP1 | |
| SCHEMBL3950341 | 0.79 | GSK3B (0.38) | LRRK2MAPTCCR1CCR5CCR8 | |
| SCHEMBL7832083 | 0.79 | KDM4E (0.36) | MEN1KMT2ACCR1CCR5CCR8 | |
| SCHEMBL28836229 | 0.79 | CCR1 (0.34) | CCR1CCR5CCR8PARP1PARP14 | |
| Hydrochloric Acid SCHEMBL28836198 | 0.78 | CYP1A2 (0.35) | CCR1CCR5CCR8PARP1PARP14 | |
| SCHEMBL4370037 | 0.78 | NOS2 (0.41) | CCR1CCR5CCR8PARP1PARP2 | |
| SCHEMBL8875881 | 0.75 | GSK3B (0.44) | PARP1CDK2ALDH1A1 | |
| SCHEMBL8214129 | 0.74 | CCNB2 (0.40) | KMT2APARP14 | |
| SCHEMBL6311538 | 0.73 | MGAM (0.47) | ALDH1A1 | |
| SCHEMBL1665498 | 0.72 | PARP1 (0.42) | CCR1CCR5CCR8PARP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050159464-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | ASSMANN LUTZ (DE) | 2005-07-21 | — | — | US | disclosed |
| CN-1633434-A | Imidazo [1, 2-a ] pyridine derivatives | DAIICHI SEIYAKU CO (JP) | 2005-06-29 | — | — | CN | disclosed |
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6271226-B1 | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159464-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | CAT, AADAC, CBR3 | LRRK2 2169/4885MAP4K1 3632/4885CYP17A1 3663/4885 |
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | LRRK2 3378/4885MAP4K1 1321/4885CYP17A1 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.