Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 15/20 | 0.47 |
| ▸ | GAA | P10253 | 15/20 | 0.47 |
| ▸ | SI | P14410 | 15/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 15/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359045 | 0.81 | MGAM (0.51) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL11574137 | 0.81 | PSMB8 (0.59) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4919548 | 0.80 | DDAH1 (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL30518181 | 0.80 | DDAH1 (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8328058 | 0.79 | PKM (0.57) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4105591 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL11749738 | 0.79 | GAA (0.40) | GAAALDH1A1TDP1ESR1 | |
| SCHEMBL7409334 | 0.78 | MGAM (0.49) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4062820 | 0.78 | MGAM (0.51) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4346855 | 0.78 | MGAM (0.51) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-4113718-A | Basic azo dyes | CIBA-GEIGY CORPORATION (US) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | MGAM 11/4885GAA 58/4885SI 562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.