Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319665 | 0.91 | KDM4E (0.46) | PTPN5POLBKDM4EALDH1A1HPGD | |
| SCHEMBL6318663 | 0.83 | SCN9A (0.40) | PTPN5POLBRAB9ASCN9APPARG | |
| SCHEMBL6319864 | 0.82 | PTPN5 (0.58) | PTPN5POLBKDM4EPSMD14RECQL | |
| SCHEMBL6319268 | 0.81 | PTPN5 (0.52) | PTPN5POLBKDM4EPSMD14RECQL | |
| SCHEMBL5881620 | 0.79 | PTPN5 (0.57) | PTPN5POLBKDM4EPSMD14RECQL | |
| SCHEMBL6326442 | 0.77 | PTPN5 (0.55) | PTPN5POLBKDM4EPSMD14RECQL | |
| SCHEMBL5881650 | 0.77 | PTPN5 (0.55) | PTPN5POLBKDM4EPSMD14RECQL | |
| SCHEMBL6325273 | 0.77 | PTPN5 (0.58) | PTPN5POLBKDM4EPSMD14RECQL | |
| SCHEMBL6322652 | 0.76 | POLB (0.61) | PTPN5POLBKDM4EPSMD14RECQL | |
| SCHEMBL5881790 | 0.76 | PTPN5 (0.58) | PTPN5POLBKDM4EPSMD14RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171185-A1 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD., A JAPANESE CORPORATION | 2005-08-04 | — | — | US | disclosed |
| US-20050025795-A1 | Compounds, Compositions and methods for insect control | THE PROCTER & GAMBLE COMPANY (US) | 2005-02-03 | — | — | US | disclosed |
| EP-1501830-A1 | 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | Actelion Pharmaceuticals Ltd. (CH) | 2005-02-02 | — | — | EP | disclosed |
| EP-1397042-A1 | COMPOSITIONS AND METHODS FOR INSECT CONTROL | THE PROCTER & GAMBLE COMPANY (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003093267-A1 | 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2003-11-13 | — | — | WO | disclosed |
| WO-2002067680-A1 | COMPOSITIONS AND METHODS FOR INSECT CONTROL | THE PROCTER & GAMBLE COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
| EP-1070705-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050025795-A1 | Compounds, Compositions and methods for insect control | PWWP2B, CUTA, WAPL | PTPN5 441/4885POLB 1565/4885KDM4E 1659/4885 |
| US-20050171185-A1 | Indole derivatives | PDE5A, IGFBP5, HTR5A | PTPN5 108/4885POLB 3673/4885KDM4E 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.