Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 9/20 | 0.52 |
| ▸ | CES1 | P23141 | 8/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20959565 | 0.82 | CES2 (0.50) | CES2CES1AKR1C1ALDH1A1MAPK1 | |
| SCHEMBL11816610 | 0.76 | CES2 (0.59) | CES2CES1AKR1C1ALDH1A1DAO | |
| SCHEMBL11816613 | 0.76 | CES2 (0.59) | CES2CES1AKR1C1ALDH1A1DAO | |
| SCHEMBL8734925 | 0.76 | CES2 (0.59) | CES2CES1AKR1C1ALDH1A1DAO | |
| SCHEMBL8734921 | 0.76 | CES2 (0.59) | CES2CES1AKR1C1ALDH1A1DAO | |
| SCHEMBL11881116 | 0.76 | CES2 (0.59) | CES2CES1AKR1C1ALDH1A1DAO | |
| SCHEMBL12396909 | 0.74 | CES2 (0.56) | CES2CES1AKR1C1ALDH1A1DAO | |
| SCHEMBL112003 | 0.74 | CES2 (0.56) | CES2CES1AKR1C1ALDH1A1DAO | |
| SCHEMBL7607185 | 0.74 | CES1 (0.39) | CES2CES1AKR1C1ALDH1A1DAO | |
| SCHEMBL27771233 | 0.74 | CES2 (0.56) | CES2CES1AKR1C1ALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960667-B2 | Fluorescent maleimides and uses thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-01 | — | — | US | disclosed |
| US-20030189191-A1 | Fluorescent maleimides and uses thereof | KUNIMOTO KAZUHIKO (JP) | 2003-10-09 | — | — | US | disclosed |
| US-6508957-B2 | Ultraviolet fluorescent material for void detection and for preparation of scintillators, films, luminescent solar energy collectors, organic electroluminescent devices, printing inks, electrophotographic toners | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-21 | — | — | US | disclosed |
| US-20020065422-A1 | Fluorescent maleimides and uses thereof | KUNIMOTO KAZUHIKO (JP) | 2002-05-30 | — | — | US | disclosed |
| US-6258954-B1 | ELECTROLUMINESCENCE; DETECTION VOIDS | CIBA SPECIALTY CHEMICALS CORP. | 2001-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065422-A1 | Fluorescent maleimides and uses thereof | IK, PAH, MYO1F | CES2 2780/4885CES1 3843/4885AKR1C1 584/4885 |
| US-20030189191-A1 | Fluorescent maleimides and uses thereof | CBR1, CBR3, MT-CO2 | CES2 288/4885CES1 239/4885AKR1C1 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.