Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.33 |
| ▸ | HPGDS | O60760 | 3/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PRKDC | P78527 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317095 | 0.63 | NPC1 (0.35) | MAOAMAOBCHRNA7ITKMAPT | |
| SCHEMBL8597630 | 0.61 | MAPT (0.45) | MAOAMAOBCHRNA7MAPTNPC1 | |
| SCHEMBL6318633 | 0.61 | MAPT (0.34) | ABL1CHRNA7HPGDSMAPTNPC1 | |
| SCHEMBL8600809 | 0.61 | CA2 (0.44) | MAOAMAOBCHRNA7MAPTNPC1 | |
| SCHEMBL4444185 | 0.60 | CA2 (0.43) | MAOAMAOBCHRNA7MAPTNPC1 | |
| SCHEMBL8600765 | 0.60 | CA2 (0.43) | MAOAMAOBCHRNA7MAPTNPC1 | |
| SCHEMBL8596068 | 0.60 | CA2 (0.43) | MAOAMAOBCHRNA7MAPTNPC1 | |
| SCHEMBL8599290 | 0.58 | CHRNA7 (0.42) | MAOAMAOBABL1CHRNA7HPGDS | |
| SCHEMBL4450281 | 0.57 | CA2 (0.48) | MAOAMAOBCHRNA7ITKMAPT | |
| SCHEMBL8598275 | 0.57 | CHRNA7 (0.39) | MAOAMAOBCHRNA7HPGDSITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | APOB, LDLR, LPL | MAOA 1895/4885MAOB 1230/4885ABL1 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.