Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596068 | 1.00 | CA2 (0.43) | CA2CHRNA7MAOAMAOBSIGMAR1 | |
| SCHEMBL4444185 | 1.00 | CA2 (0.43) | CA2CHRNA7MAOAMAOBSIGMAR1 | |
| SCHEMBL8600809 | 0.99 | CA2 (0.44) | CA2CHRNA7MAOAMAOBSIGMAR1 | |
| SCHEMBL8626160 | 0.85 | MAPT (0.43) | CA2CHRNA7NPC1MAPTRAB9A | |
| SCHEMBL8599290 | 0.85 | CHRNA7 (0.42) | CA2CHRNA7MAOAMAOBNPC1 | |
| SCHEMBL8598275 | 0.83 | CHRNA7 (0.39) | CA2CHRNA7MAOAMAOBNPC1 | |
| SCHEMBL8598239 | 0.83 | CA2 (0.39) | CA2CHRNA7NPC1MAPTRAB9A | |
| SCHEMBL8597630 | 0.79 | MAPT (0.45) | CA2CHRNA7MAOAMAOBNPC1 | |
| SCHEMBL6311972 | 0.76 | ALDH1A1 (0.46) | CHRNA7MAPT | |
| SCHEMBL10686711 | 0.72 | OPRD1 (0.49) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641791-B1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5472962-A | Antiestrogenic agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| EP-0641791-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |