Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596068 | 0.99 | CA2 (0.43) | CA2CHRNA7SIGMAR1MAOAMAOB | |
| SCHEMBL8600765 | 0.99 | CA2 (0.43) | CA2CHRNA7SIGMAR1MAOAMAOB | |
| SCHEMBL4444185 | 0.99 | CA2 (0.43) | CA2CHRNA7SIGMAR1MAOAMAOB | |
| SCHEMBL8599290 | 0.86 | CHRNA7 (0.42) | CA2CHRNA7CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8598275 | 0.85 | CHRNA7 (0.39) | CA2CHRNA7MAOAMAOBNPC1 | |
| SCHEMBL8598239 | 0.84 | CA2 (0.39) | CA2CHRNA7CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8626160 | 0.83 | MAPT (0.43) | CA2CHRNA7CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8597630 | 0.80 | MAPT (0.45) | CA2CHRNA7MAOAMAOBNPC1 | |
| SCHEMBL6311972 | 0.78 | ALDH1A1 (0.46) | CHRNA7BACE1MAPT | |
| SCHEMBL1628516 | 0.73 | CYP1A2 (0.46) | CYP1A2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641791-B1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5472962-A | Antiestrogenic agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| EP-0641791-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |