SCHEMBL6320646

SCHEMBL6320646

CCCOC(=O)C(F)(F)C(=O)CF

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.35
HCAR2 Q8TDS4 1/20 0.34
ALDH1A1 P00352 3/20 0.33
FAAH O00519 8/20 0.32
LMNA P02545 1/20 0.32
ESR1 P03372 1/20 0.32
CHRM1 P11229 1/20 0.32
TSHR P16473 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDR P35968 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CES1 P23141 5/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10451649 0.89 ALDH1A1 (0.45) CES2HCAR2ALDH1A1FAAHESR1
SCHEMBL6323107 0.85 CES2 (0.50) CES2HCAR2FAAHTSHRCES1
SCHEMBL457731 0.83 PKM (0.40) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL6327476 0.83 ALDH1A1 (0.47) CES2ALDH1A1TSHR
SCHEMBL6328254 0.82 ALDH1A1 (0.46) CES2ALDH1A1TSHR
SCHEMBL7406644 0.82 PKM (0.39) ALDH1A1LMNAMEN1KMT2AHSD17B10
Water SCHEMBL10546251 0.82 MEN1 (0.40) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL27959199 0.78 HCAR2 (0.35) CES2HCAR2ALDH1A1LMNAESR1
Trifluoroacetic Acid SCHEMBL9068008 0.77 CYP4F2 (0.36) ALDH1A1LMNAMEN1KMT2AHSD17B10
SCHEMBL3289502 0.76 CES2 (0.41) CES2HCAR2ALDH1A1FAAHLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417719-B Application of titanium chelate as reaction catalyst for synthesizing benzyl carbonate or diphenyl carbonate by ester exchange 华东理工大学 2022-11-25 CN disclosed
US-6893861-B1 Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives LONZA AG (CH) 2005-05-17 US disclosed