Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL9068008

CCOC(=O)C(F)(F)C(=O)CF.O=C(O)C(F)(F)F

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
PKM P14618 2/20 0.36
THRB P10828 1/20 0.36
POLB P06746 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HTT P42858 1/20 0.35
PIN1 Q13526 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 3/20 0.33
HDAC4 P56524 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457731 0.92 PKM (0.40) CYP4F2CYP4A11PKMTHRBPOLB
SCHEMBL7406644 0.90 PKM (0.39) CYP4F2CYP4A11PKMTHRBPOLB
Water SCHEMBL10546251 0.90 MEN1 (0.40) CYP4F2CYP4A11PKMTHRBPOLB
SCHEMBL3372776 0.80 ALDH1A1 (0.42) CYP4F2CYP4A11PKMTHRBPOLB
Trifluoroacetic Acid SCHEMBL10523981 0.80 ALDH1A1 (0.42) CYP4F2CYP4A11PKMTHRBPOLB
Fluoride SCHEMBL11204021 0.78 ALDH1A1 (0.40) CYP4F2CYP4A11PKMTHRBPOLB
SCHEMBL13807718 0.78 SOAT1 (0.42) CYP4F2CYP4A11PKMTHRBPOLB
SCHEMBL1979744 0.77 ALDH1A1 (0.48) CYP4F2CYP4A11PKMTHRBPOLB
SCHEMBL6320646 0.77 CES2 (0.35) MEN1KMT2AALDH1A1LMNAHSD17B10
SCHEMBL6327476 0.76 ALDH1A1 (0.47) THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5481029-A Process for preparation of ketones SOLVAY FLUOR UND DERIVATE GMBH (DE) 1996-01-02 US disclosed