SCHEMBL457731

SCHEMBL457731

CCOC(=O)C(F)(F)C(=O)CF

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.40
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
THRB P10828 1/20 0.40
HTT P42858 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 2/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7406644 0.98 PKM (0.39) PKMCYP4F2CYP4A11THRBHTT
Water SCHEMBL10546251 0.98 MEN1 (0.40) PKMCYP4F2CYP4A11THRBHTT
Trifluoroacetic Acid SCHEMBL9068008 0.92 CYP4F2 (0.36) PKMCYP4F2CYP4A11THRBHTT
SCHEMBL13807718 0.84 SOAT1 (0.42) PKMCYP4F2CYP4A11THRBHTT
SCHEMBL1979744 0.84 ALDH1A1 (0.48) PKMCYP4F2CYP4A11THRBHTT
SCHEMBL6320646 0.83 CES2 (0.35) ALDH1A1MEN1KMT2ALMNAHSD17B10
SCHEMBL6327476 0.83 ALDH1A1 (0.47) THRBALDH1A1
SCHEMBL6328254 0.81 ALDH1A1 (0.46) CYP4F2CYP4A11THRBALDH1A1
SCHEMBL7914245 0.81 CYP4F2 (0.39) PKMCYP4F2CYP4A11THRBHTT
SCHEMBL6718702 0.81 MMP8 (0.44) PKMCYP4F2CYP4A11THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 820 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036534-A Synthetic method and raw material recovery method of enamine compound 山东潍坊润丰化工股份有限公司 2026-05-15 CN claimed
CN-120149502-A Secondary battery 珠海冠宇电池股份有限公司 2025-06-13 CN claimed
CN-119930957-A Trifluoro acetyl piperazine modified polyarylpiperidine film, preparation method thereof and application thereof in neutral organic flow battery 中盐金坛盐化有限责任公司 2025-05-06 CN claimed
CN-116410138-B Pyricularia sulfone Synthesis method of intermediate 山东润博生物科技有限公司 2025-05-06 CN claimed
CN-115850178-B Preparation method of 1-methyl-3- (trifluoromethyl) -1H-pyrazol-5-ol 宁夏格瑞精细化工有限公司 2025-04-04 CN claimed
CN-119463802-A Room temperature vulcanized silicone sealant for yellowing-resistant bulb lamp and preparation method thereof 宁波聚力新材料科技有限公司 2025-02-18 CN claimed
CN-119318925-A Continuous production system and continuous production method of 5- (difluoromethoxy) -4-chloromethyl-1-methyl-3- (trifluoromethyl) -1H-pyrazole 天津凯莱英医药科技发展有限公司 2025-01-17 CN claimed
CN-118988201-A Production method and equipment of ethyl trifluoroacetoacetate 济南万兴达化工有限公司 2024-11-22 CN claimed
CN-118955469-A Pyrazole alcohol compound as well as preparation method and application thereof 安徽中医药大学 2024-11-15 CN claimed
CN-118834189-A Light-induced fluorescence excitation probe, indazolone compound, and preparation methods and applications thereof 国科大杭州高等研究院 2024-10-25 CN claimed
EP-0135491-B1 HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS MONSANTO COMPANY (US) 1989-01-25 EP claimed
EP-0158399-B1 LIQUID COATING COMPOSITION FOR PRODUCING HIGH QUALITY, HIGH PERFORMANCE FLUORINE-DOPED TIN OXIDE COATINGS M & T CHEMICALS, INC. (US) 1988-11-02 EP claimed
EP-0206953-B1 PROCESS FOR THE PREPARATION OF ETHYL TRIFLUOROACETOACETATE RHONE-POULENC CHIMIE (FR) 1988-09-07 EP claimed
EP-0270724-A1 Preparation of alkyl trifluoroacetoacetate Monsanto Company (US) 1988-06-15 EP claimed
US-4731256-A Liquid coating composition for producing high quality, high performance fluorine-doped tin oxide coatings M&T CHEMICALS INC. (US) 1988-03-15 US claimed
US-4696837-A Chemical vapor deposition method of producing fluorine-doped tin oxide coatings M&T CHEMICALS INC. (US) 1987-09-29 US claimed
US-4647689-A Preparation of alkyl trifluoroacetoacetate MONSANTO COMPANY (US) 1987-03-03 US claimed
US-4601917-A CHEMICAL VAPOR DEPOSITION M&T CHEMICALS INC. (US) 1986-07-22 US claimed
EP-0135491-A1 Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters MONSANTO COMPANY (US) 1985-03-27 EP claimed
US-4026898-A 7-Oxo-1,2,3,3,8-pentamethyl-5-trifluoromethyl-2,3,7,8-tetrahydro-1-H-pyrrolo[3,2-g]q THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-05-31 US claimed