Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313731 | 0.87 | PIK3CA (0.41) | NPSR1RAB9AKMT2ADHFRPIK3CA | |
| SCHEMBL6318862 | 0.82 | DHFR (0.56) | NPSR1DHFRPIK3CA | |
| SCHEMBL6318945 | 0.82 | TNF (0.44) | MAPTNPSR1EGFRSMN1; SMN2KMT2A | |
| SCHEMBL6315288 | 0.80 | PDGFRB (0.49) | NPSR1FAAHRAB9ASMN1; SMN2PIK3CA | |
| SCHEMBL6315312 | 0.80 | IGF1R (0.54) | EGFRMAOB | |
| SCHEMBL6321509 | 0.80 | IGF1R (0.60) | EGFR | |
| SCHEMBL6312550 | 0.78 | CA12 (0.56) | EGFRERBB2FAAHRAB9AKMT2A | |
| SCHEMBL6313258 | 0.76 | DYRK1A (0.43) | NPSR1DHFRPIK3CA | |
| SCHEMBL6313300 | 0.75 | ABCG2 (0.46) | NPSR1EGFRDHFRPIK3CA | |
| SCHEMBL6315310 | 0.75 | ADORA1 (0.45) | EGFRSMN1; SMN2KMT2ADHFRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580191-A1 | PROCESS FOR PRODUCING CARBAPENEM COMPOUND FOR ORAL ADMINISTRATION | KANEKA CORPORATION (JP) | 2005-09-28 | — | — | EP | disclosed |
| US-6939874-B2 | Substituted pyrimidinyl derivatives and methods of use | AMGEN INC. (US) | 2005-09-06 | — | — | US | disclosed |